Abstract: Centrifuge model tests on sand slopes were carried out on a centrifuge shaking table to investigate the seismic behavior of pile-reinforced slope and soil-pile interaction.The adjusted El Centro earthquake was excited as the input motion under 50g centrifugal accelerations.Acceleration time histories at different locations were recorded and analyzed in the frequency domain.Dynamic soil pressure and vertical strain along the piles were also recorded.It was indicated that the seismic response of the slopes was amplified as the earthquake motion propagated upwards.The response of adjacent soil was impeded by stabilizing piles to a certain degree.Along with the excitation of earthquake motion,the dynamic soil pressure rapidly increased to the peak value and then kept roughly stable until the end of the motion.The bending moment of the piles performed similar variation and the maximum moment occurred at the lower section of the piles.