Abstract: Stability of high lithological slope was is of complex problems in highway construction in mountainous area and hilly country,which is a complicated system engineering problem,and can mot be solved by simple mathematical and mechanical methods.On the basis of geological and environmental conditions,comprehensive analysis and evaluation with integrate mode should be the best method used for its research and solution.Stereographic projection method,Sarma method and Finite-Element Method(FEM) were used to comprehensively evaluate and integratively analyze some high lithological slope of Zhangzhou-Longyan Expressway,which procured ideal conclusions and were accepted and adopted by design and execution departments.This project practice for several years safe operation after completion shows that the comprehensive evaluation and integrated analysis method is successful and effective,and should be an important way of stability evaluation of high lithological slope of expressway.