Abstract: Using the multi-function testing machine named RMT150B,the fatigue life of rock due to different affecting factors under uniaxial compression condition were studied.It was emphasized that the fatigue life of rock sample was influenced by stress amplitudes,waveforms and frequencies.The essential reason of influence of stress amplitudes and waveforms on rock life was different dissipation of energy.And the essential reason of influence of different frequencies on rock life was different rate of loading.