Abstract: In order to reasonably simulate the anisotropy and creep of rock and soil, the models of transversely isotropic visco elasticity in back analysis with staged construction are established for layered rock and soil. In the typical deep excavation of Shanghai, this model is adopted with the genetic algorithm. The parameters back calculated such as elastic modulus and creep coefficients are used to predict deformation and internal force of structure in the next stages, so this provides a new methods for feedback design and informationalized construction and is helpful to the development of back analysis.