Abstract: The pile foundation is widely used in offshore engineering, for example, the large-diameter steel pipe pile is mostly used in offshore wind motor. However, due to the large weight of piles and hammers, the phenomenon of pile running may occur in the process of pile driving, which is easy to damage the piles and hammers, seriously affecting the efficiency of pile driving, and may cause serious safety accidents. Therefore, it is of practical significance to analyze the causes of pile running and propose a reasonable calculation method of bearing capacity. The mechanism of pile running is investigated. The cone penetration tests-based ICP-05 and UWA-05 design methods are used to analyze and calculate the bearing capacity of large-diameter steel pipe piles of offshore wind power at the depth of pile running. It is found that the ICP-05 method is ideal in calculating the bearing capacity of the large-diameter steel pipe piles of offshore wind power. A reduction optimization formula based on the concept of influence zone is proposed, and the rationality of the optimization design method is verified by calculating the bearing capacity of pile-running depth.