Abstract: Based on the shaking table tests on frozen soil-structure dynamic interaction system, the earthquake damage phenomenon of the superstructure and foundation of frozen soil site and the liquefaction phenomenon of sandy silt under earthquake excitation are reproduced by using the self-made indoor frozen soil freezing system, the seismic response of frozen soil sites with different freezing depths and its influence on the seismic response of superstructure are in vestigated. In addition, a nonlinear model considering the dependence of frozen soil on temperature and the change of equivalent shear stiffness caused by liquefaction of foundation is established by using the nonlinear finite element software, which lays a foundation for the subsequent calculation and analysis. The analysis shows that the seismic response and the peak frequency of the surface decrease with the increase of the input seismic waves due to the non-linear progress of the soil. The interaction between the superstructure and the foundation is obvious, the amplitude of ground surface decreases with the increase of the freezing depth, and the seismic response and the peak frequency of superstructure increase. The above results can provide reference for the study on frozen soil-structure dynamic interaction in seasonal frozen areas.