Abstract: The conventional seismic design of metro stations is to select the mid-span section for calculation analysis and design based on plane problem. However, the spatial effect of end walls must be considered because the area close to the front and rear end walls will inevitably be affected by the end walls and running tunnels. This effect is also called the end wall effect. The rationality of the numerical model is verified based on the numerical simulation of shaking table tests on metro stations and running tunnels firstly. Then a series of parameter analysis is performed on the spatial influence scope of the end wall of the metro station structures, which mainly includes the influences of the number of spans and layers of the metro station structures, soil parameters, seismic wave types and amplitudes, and the number of running tunnels. The calculation and analysis results show that the number of spans, the number of layers and the number of tunnels of the station structures will have certain effect on end walls influence scope. The largest influence area of end wall is the station with 2 layers and 3 spans, and the influence range is 1.6B (B is the structure width). The influence range of end wall effect is related to their own structural characteristics, but they are less affected by the soil parameters and seismic wave types and amplitudes. At the same time, the comparative analysis shows that it is more reasonable to use column end bending moment as evaluation indexes for end wall influence range analysis.