Abstract: The maximum running speed of the newly built Z2 metro line in Tianjin Binhai New Area can reach 120 km/h, which is higher than that of the ordinary metro train running in the cities (about 60~80 km/h). Compared with the ordinary train load, the load of high-speed metro has the characteristics of high frequency and large amplitude, and the environmental vibration caused by it is also different. Taking the first phase of Tianjin Z2 metro line project as an example and based on the actual engineering data, by using the large-scale general finite element software ABAQUS, the three-dimensional finite element model for rail track-tunnel-foundation-building is established, and the moving loads are simulated with ABAQUS self-contained subroutine DLOAD. The influences of rapid metro operation in Tianjin Binhai New Area in soft soil areas on the vibration of buildings along the line are analyzed using the dynamic implicit analysis. At the same time, the vibration response laws of three kinds of foundation structures of pile foundation, raft foundation and strip foundation under different train speeds and tunnel buried depth conditions are compared. The conclusions can provide guidance for the prediction and evaluation of vibration along metro lines in the future.