Abstract: In order to determine the sensitive parameters of embankment deformation behavior for coarse-grained sulfate saline soil, the quantitative analysis model for the correlation sensitive parameters is proposed, and the relevant influence factors and the quantitative indexes of the interaction between the factors of coarse-grained sulfate saline soil are investigated. Based on the single-factor salt expansion test results, the salt expansion tests under the interaction of multiple factors are performed using the orthogonal design method. And the simplified prediction models for salt expansion rate of coarse-grained sulfate saline soil are established. The sensitive parameters for the deformation behavior of coarse-grained sulfate saline soil are studied through stepwise regression analysis of SPSS. The results show that the quantitative indexes of the sensitive factors are salt (46%~37%), load (43%~29%), water (12%~6%), interaction of salt and load (7.6%), interaction of salt and water (2%) in turn. The soluble salt on salt expansion is promoted. Due to different salt contents, the water will have a change in the role of salt expansion rate. The load, interaction of salt and load, interaction of salt and water have a certain inhibitory effect on the salt expansion. The initial compaction degree has a certain effect on the salt expansion rate, but it has no significant effect on the salt expansion rate in the range of 97% ~ 89% due to its special characteristics.