Abstract: A deep excavation project of Wuhan Metro is taken as the research background, and several methods such as site monitoring, BP neural network prediction and numerical simulation are combined to investigate the deformation rules of the support structure of metro station in a complex road section and the effect of deep foundation pit excavation on overpass viaduct piers. In this study, the numerical simulation method is proposed to be used for dynamic rehearsal of engineering construction in similar future projects so as to verify the safety and economical efficiency of design schemes of excavations; meanwhile, dynamic prediction can be realized via BP neural network during construction to know the deformation trend at the next stage of such construction so as to establish informationization construction monitoring schemes combining “simulation and prediction” and to achieve safe and economical construction.