Abstract: The spatial structure of overlying strata of deep irregular island face under thick topsoil is complex, and the movement of its roof is drastic. Mine bumping in this kind of isolated island is easy to occur under the influence of mining depth and geological structure. Through a case study of one deep mine irregular island face project, safe mining of this island face is ensured through the following steps: firstly, the hazard of mine pressure bumping is evaluated, based on the simulations by mining before advancing and the strata spatial structure theory; secondly, the on-line stress monitoring system and drilling cuttings method are adopted for risk inspection and forecast; finally, the technology of drilling and blasting pressure releasing is adopted to deal with dangerous areas. Based on this study, the safe mining of this complex spatial structure is effectively guaranteed.